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| Cancer News |
 August 2009 Volume 11, Number 8 |
Cover Illustration: The cover is an artistic rendering of results presented in the paper by Ciuffreda et.al., wherein a novel MEK inhibitor was shown to have anti-tumor activity in melanoma, irrespective of their BRAF status. |
TABLE OF CONTENTS
Research Article |
| Growth-inhibitory and anti-angiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations |
| Ludovica Ciuffreda, Donatella Del Bufalo, Marianna Desideri, Cristina Di Sanza, Antonella Stoppacciaro, Maria Rosaria Ricciardi, Sabina Chiaretti, Simona Tavolaro, Barbara Benassi, Alfonso Bellacosa, Robin Foà, Agostino Tafuri, Francesco Cognetti, Andrea Anichini, Gabriella Zupi and Michele Milella |
| Abstract Full Article |
| Platelet derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo |
| Debora Faraone, Maria Simona Aguzzi, Gabriele Toietta, Angelo M Facchiano, Francesco Facchiano, Alessandra Magenta, Fabio Martelli, Silvia Truffa, Eleonora Cesareo, Domenico Ribatti, Maurizio C Capogrossi and Antonio Facchiano |
| Abstract Full Article |
| Small molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma |
| Sriharikrishna Vellanki, Andreas Gabrucker, Stefan Liebau, Christian Proepper, Adriana Eramo, Veit Braun, Tobias Böckers, Klaus-Michael Debatin and Simone Fulda |
| Abstract Full Article |
| Mdm2 deficiency suppresses MYCN-driven neuroblastoma tumorigenesis in vivo |
| Zaowen Chen, Yunfu Lin, Eveline Barbieri, Sue Burlingame, John Hicks, Andrew Ludwig and Jason M Shohet |
| Abstract Full Article |
| Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients |
| Ruo-Chia Tseng, Chin-Chu Lee, Han-Shui Hsu, Ching Tzao and Yi-Ching Wang |
| Abstract Full Article |
| Circulating endothelial cells and circulating progenitor cells in breast cancer Relationship to endothelial damage/dysfunction/apoptosis, clinico-pathological factors, and the Nottingham prognostic index |
| Patrick Goon, Gregory YH Lip, Paul S Stonelake and Andrew Blann |
| Abstract Full Article |
| Development, characterization, and immunotherapeutic utilization of peptide mimics of the thomsen-friedenreich carbohydrate antigen |
| Jamie Heimburg-Molinaro, Adel Almogren, Susan Morey, Olga V. Glinskii, Rene Roy, Gregory E. Wilding, Richard P. Cheng, Vladislav V. Glinsky and Kate Rittenhouse-Olson |
| Abstract Full Article |
| Neurophil influx and chemokine production during the early phases of the anti-tumor response to the vascular disrupting agent (DMXAA (ASA404) |
| Liang-Chuan S Wang, Lotte Thomsen, Rachel Sutherland, Charu B Reddy, Sofian M Tijono, Chun-Jen J Chen, Catherine E Angel, Rod Dunbar and Lai-Ming Ching |
| Abstract Full Article |
| N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer |
| Dorothee Pflueger, David S Rickman, Andrea Sboner, Sven Perner, Christopher J LaFargue, Maria A Svensson, Benjamin J Moss, Naoki Kitabayashi, Yihang Pan, Alexandre de la Taille, Rainer Kuefer, Ashutosh K Tewari, Francesca Demichelis, Mark S Chee, Mark B Gerstein and Mark A Rubin |
| Abstract Full Article |
| Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model |
| Matthias Hofmann, Emmet McCormack, Maja Mujic, Maila Roßberg, August Bernd, Jürgen Bereiter-Hahn, Björn T Gjertsen, Helge Wiig and Stefan Kippenberger |
| Abstract Full Article |
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