An International Journal for Oncology Research.  

 


May 2010
Volume 12, Number 5
Cover Illustration:
The cover represents an artistic depiction of the results from the paper by Hembruff et al., wherein loss of Transforming Growth Factor-β signaling in mammary fibroblasts was shown to enhance CCL2 secretion to promote mammary tumor progression through macrophage-dependent and -independent mechanisms.

TABLE OF CONTENTS

Research Article

GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer
Richard L Watson, Aaron C Spalding, Steven P Zielske, Meredith Morgan, Alex C Kim, Guido T Bommer, Hagit Eldar-Finkelman, Thomas Giordano, Eric R Fearon, Gary D Hammer, Theodore S Lawrence and Edgar Ben-Josef
Abstract   Full Article

The rGel/BLyS fusion toxin inhibits diffuse large B cell lymphoma growth in vitro and in vivo
Mi-Ae Lyu, Deepak Rai, Kwang Seok Ahn, Bokyung Sung, Lawrence H. Cheung, John W. Marks, Bharat B. Aggarwal, Ricardo C.T. Aguiar, Varsha Gandhi and Michael G Rosenblum
Abstract   Full Article

Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells
Pei-Chih Lee, Rajesh Kakadiya, Tsann-Long Su and Te-Chang Lee
Abstract   Full Article

Comparison of tumor and microenvironment secretomes in plasma and in platelets during prostate cancer growth in a xenograft model
Bethany A Kerr, Ranko Miocinovic, Armine K Smith, Eric A Klein and Tatiana V Byzova
Abstract   Full Article

3D-specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model
Toshiyuki Tsunoda, Yasuo Takashima, Takahiro Fujimoto, Midori Koyanagi, Yasuhiro Yoshida, Keiko Doi, Yoko Tanaka, Tanaka, Masahide Kuroki, Takehiko Sasazuki and Senji Shirasawa
Abstract And Supplemental Data   Full Article

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression
Kyle Lafferty-Whyte, Alan Bilsland, Stacey F Hoare, Sharon Burns, Nadia Zaffaroni, Claire J Cairney and Nicol Keith
Abstract   Full Article

Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft via down-regulation of beta-catenin-dependent signaling
Manjinder Kaur, Balaiya Velmurugan, Alpna Tyagi, Chapla Agarwal, Rana Singh and Rajesh Agarwal
Abstract   Full Article

Loss of TGF-beta signaling in mammary fibroblasts enhances CCL2 secretion to promote mammary tumor progression through macrophage dependent and independent mechanisms
Stacey L Hembruff, Iman Jokar, Li Yang and Nikki Cheng
Abstract   Full Article

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