An International Journal for Oncology Research.  

 


June 2010
Volume 12, Number 6
Cover Illustration:
The cover represents an artistic depiction of the results presented in the paper by van Houdt et al., wherein a causal role for oncogenic KRAS in desensitizing tumor cells to EGFR activation and inhibition.

TABLE OF CONTENTS

Research Article

Cancer immunoediting from immunosurveillance to tumour escape in microvillus-formed niche. A study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer
Carl-Jørgen Arum, Endre Anderssen, Trond Viset, Yosuke Kodama, Steinar Lundgren, Duan Chen and Chun Mei Zhao
Abstract   Full Article

Oncogenic KRAS desensitizes colorectal tumor cells to EGFR inhibition and activation
Winan J van Houdt, Frederik Hoogwater, Menno de Bruijn, Benjamin Emmink, Maarten Nijkamp, Petra van der Groep, Paul van Diest, Inne Borel Rinkes, Onno Kranenburg and Danielle A Raats
Abstract   Full Article

Invasive glioblastoma cells acquire stemness and increased Akt activation
Jennifer Molina, Yuho Hayashi, Clifton Stephens and Maria-Magdalena Georgescu
Abstract   Full Article

Teriflunomide (Leflunomide) promotes cytostatic, antioxidant, and apoptotic effects in transformed prostate epithelial cells: Evidence supporting a role for teriflunomide in prostate cancer Chemoprevention
Numsen Hail, Jr., Ping Chen and Lane R. Bushman
Abstract   Full Article

SCCRO promotes glioma formation and malignant progression in mice
Stephen Broderick, Benjamin J Golas, Duykhanh Pham, Christopher W Towe, Simon G Talbot, Andrew Kaufman, Sarina Bains, Laryssa A Huryn, Yoshihiro Yonekawa, Diane Carlson, Dolores Hambardzumyan, Yegnanarayana Ramanathan and Bhuvanesh singh
Abstract   Full Article

Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner
Claudia D Andl, Kelsey M McCowan, Gillian L Allison and Anil K Rustgi
Abstract   Full Article

A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent and associated with survival in human lung adenocarcinomas
Humam Kadara, Junya Fujimoto, Taoyan Men, Xiaofeng Ye, Dafna Lotan, Ju-Seog Lee and Reuben Lotan
Abstract And Supplemental Data   Full Article

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