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June 2010 Volume 12, Number 6
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Cover Illustration:
The cover represents an artistic depiction of the results presented in the paper by van Houdt et al., wherein a causal role for oncogenic KRAS in desensitizing tumor cells to EGFR activation and inhibition.
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TABLE OF CONTENTS
Research Article |
| Cancer immunoediting from immunosurveillance to tumour escape in microvillus-formed niche. A study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer |
| Carl-Jørgen Arum, Endre Anderssen, Trond Viset, Yosuke Kodama, Steinar Lundgren, Duan Chen and Chun Mei Zhao |
| Abstract Full Article |
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| Oncogenic KRAS desensitizes colorectal tumor cells to EGFR inhibition and activation |
| Winan J van Houdt, Frederik Hoogwater, Menno de Bruijn, Benjamin Emmink, Maarten Nijkamp, Petra van der Groep, Paul van Diest, Inne Borel Rinkes, Onno Kranenburg and Danielle A Raats |
| Abstract Full Article |
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| Invasive glioblastoma cells acquire stemness and increased Akt activation |
| Jennifer Molina, Yuho Hayashi, Clifton Stephens and Maria-Magdalena Georgescu |
| Abstract Full Article |
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| Teriflunomide (Leflunomide) promotes cytostatic, antioxidant, and apoptotic effects in transformed prostate epithelial cells: Evidence supporting a role for teriflunomide in prostate cancer Chemoprevention |
| Numsen Hail, Jr., Ping Chen and Lane R. Bushman |
| Abstract Full Article |
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| SCCRO promotes glioma formation and malignant progression in mice |
| Stephen Broderick, Benjamin J Golas, Duykhanh Pham, Christopher W Towe, Simon G Talbot, Andrew Kaufman, Sarina Bains, Laryssa A Huryn, Yoshihiro Yonekawa, Diane Carlson, Dolores Hambardzumyan, Yegnanarayana Ramanathan and Bhuvanesh singh |
| Abstract Full Article |
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| Cathepsin B is the driving force of esophageal cell invasion in a fibroblast-dependent manner |
| Claudia D Andl, Kelsey M McCowan, Gillian L Allison and Anil K Rustgi |
| Abstract Full Article |
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| A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent and associated with survival in human lung adenocarcinomas |
| Humam Kadara, Junya Fujimoto, Taoyan Men, Xiaofeng Ye, Dafna Lotan, Ju-Seog Lee and Reuben Lotan |
| Abstract And Supplemental Data Full Article |
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